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2021

April 30th

  • Stromal Wnt Activity and Function in Chronic Inflammatory States by Dr. Alisa Mueller

  • Noninvasive ultrasound of the spleen to treat inflammatory diseases by Dr. Bryce Binstadt

             Location: Zoom
             Time: 12:30-1:30 p.m.

March 26th

  • Immune Checkpoint Inhibitor Treatment in Cancer: Immunomodulator Use and Evaluation by Rheumatology by Dr. Kiki Cunningham-Bussel 

  • Cell-mediated cytotoxicity in Lyme arthritis by Dr. Allen Steere

             Location: Zoom
             Time: 12:30-1:30 p.m.

February 26th

  • Rheumatoid arthritis studies using the Mass General Brigham Biobank by Dr. Jeffrey Sparks

  • From bedside to benchtop: reverse translational approaches to studying kidney macrophages in lupus nephritis by Dr. Paul Hoover

             Location: Zoom
             Time: 12:30-1:30 p.m.

January 29th

  • JBC 2021: New synergies with the Boston Children’s Hospital Division of Immunology by Dr. Peter Nigrovic

  • What’s in a cell? Vectors of immune cell heterogeneity by Dr. Ricardo Grieshaber-Bouyer

             Location: Zoom
             Time: 12:30-1:30 p.m.

2020

December 20th

  • Intrinsic roles of citrullination in health and disease by Dr. I-Cheng Ho

  • Serologic diagnosis of Lyme disease in Pedi Lyme Net by Dr. Lise Nigrovic and Felix Radtke

             Location: Zoom
             Time: 12:30-1:30 p.m.

November 20th

  • Epidemiologic Clues to the Etiology of SLE by Dr. Karen Costenbader

  • Immunophenotyping as an ‘immune function test by Dr. Deepak Rao

             Location: Zoom
             Time: 12:30-1:30 p.m.

October 30th

  • Osteoarthritis and Inflammation by Dr. Lindsey Macfarlane

  • From genetic sequences to bDMARD sequences by Dr. Katherine Liao

             Location: Zoom
             Time: 12:30-1:30 p.m.

September 18th

  • Steps toward understanding human axial spondyloarthritis by Dr. Joerg Ermann

  • Phenotyping and studying heart failure in rheumatoid arthritis patients in the EHR by Dr. Selena Huang

             Location: Zoom
             Time: 12:30-1:30 p.m.

June 26th

  • Using CRISPR-Cas Technologies to Investigate the Genetics of Autoimmune Diseases by Yuriy Baglaenko

  • TARGET: An RCT in RA with Great Biospecimens by Dr. Daniel Solomon

             Location: Zoom
             Time: 12:30-1:30 p.m.

May 22nd

  • Cellular heterogeneity and lineage restriction during mouse digit tip regeneration by Dr. Jessica Lehoczky

  • How many kinds of neutrophils are there? by Ricardo Grieshaber

             Location: Zoom
             Time: 12:30-1:30 p.m.

April 17th

  • The COPPAR program by Dr. Joseph Merola and Dr. Nancy Shadick

  • Projects relating to OA and meniscal tear by Dr. Jeffrey Katz

             Location: Zoom
             Time: 12:30-1:30 p.m.

January 31st

  • The role of the intracellular DNA sensor STING in bone homeostasis by Dr. Susan MacLauchlan

  • What inter-individual differences in T cell activation can tell us about autoimmune disease mechanisms by Dr. Maria Gutierrez-Archelus

             Location: Marshall A. Wolfe Conference Room, 60 Fenwood Rd, Boston, MA 02115
             Time: 12:30-1:30 p.m.

2019

December 20th

  • Natural killer cell functions from a rheumatological perspective by Dr. Wolfgang Merkt

  • Novel anti-fibrotic therapies for Systemic Sclerosis by Dr. David Lagares

    Location: Marshall A. Wolfe Conference Room, 60 Fenwood Rd, Boston, MA 02115
    Time: 12:30-1:30 p.m.

November 22nd

  • Stability of the CD4 T Cell Receptor β chain (TCRB) Repertoire in the Joints of Oligoarticular Juvenile Idiopathic Arthritis Patients by Dr. Amelie Jule

  • Revisiting the Safety of Methotrexate: Update Based on Data From the CIRT Trial by Dr. Elizabeth Karlson

          Location: Marshall A. Wolfe Conference Room, 60 Fenwood Rd, Boston, MA 02115
          Time: 12:30-1:30 p.m.

October 25th

  • JBC Year 4 by Dr. Peter Nigrovic

  • Single cell transcriptomic and proteomic profiling of lung and synovium in rheumatoid arthritis by Drs. Kevin Wei and Fan Zhang

          Location: Bayles Conference Room, 15 Francis Street, Boston, MA 02115
          Time: 12:30-1:30 p.m.

March 22nd

  • CyTOF analyses of knowns and unknown by Dr. Deepak Rao

  • Gut microbiota, IGF-1 and Skeletal Growth by Dr. Julia Charles

Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.

February 15th

  • Physiological and Pathological Roles of Protein Citrullination by I-Cheng Ho

  • Grant Aims 2018 by Dr. Lindsey Macfarlane

Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.

January 25th

  • Finding mediators of the response to TNF and IL-17: RNA-seq with time-series, dose-response, and gene silencing by Kamil Slowikowski

  • Biomarkers and Genetics of Rheumatoid Arthritis-associated Interstitial Lung Disease  by Dr. Tracy Doyle

Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.

2018

December 21st

  • AERD- Aspirin-Exacerbated Respiratory Disease by  Dr. Tanya Laidlaw

  • Leveraging Cytometry by Time of Flight Technology: Analyzing murine bone marrow in neutropenic sepsis  by Dr. Julie Ng

Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.

November 30th

  • The Childhood Arthritis & Rheumatology Research Alliance by  Dr. Mary Beth Son

  • Deficiency of adenosine deaminase 2 (DADA2)- Monogenic vasculitis and beyond  by Dr. Pui Lee

Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
Time: 12:30-1:30 p.m.

September 28

  • RNA sequencing of monocyte subsets from blood and synovial fluid by Dr. Daimon Simmons

  • Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.
  • May 25th

    • Software for Quantitative Image Assessment of Musculoskeletal Diseases: A Tasting Menu of Methodologies by  Dr. Jeffrey Duryea

    • All of Us Research Program by Dr. Elizabeth Karlson

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    April 10th

    JBC’s Second Annual Visiting Speaker: Dr. Hermine Brunner

    • Rheumatology Grand Rounds

      Update Of Lupus Nephritis Diagnosis & Therapy In Children

      Location:  Room 03002- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 8:00-9:00 a.m.
    • Patient Care Rounds

      Comprehensive Quality Driven Care of Adolescents with Lupus

      Location:  Room 5010- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.

    February 16th

    • “BRI Single Cell Genomics Core” by Dr. Kevin Wei

    Location:  Room 03002- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    January 19th

    • Regulatory roles of citrullination in the differentiation/function of Th cells by Dr. I-Cheng Ho

    • A pilot study of dual-energy CT scan in pseudogout by Dr.Sara Tedeschi

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    2017

    December 15th

    • VERITY by Drs. Daniel Solomon, M.D., M.P.H. and Jeffrey Sparks

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    November 17th 

    • Rheumatoid Arthritis: Hypercitrullinated Cells and Consequences Dr. Nishant Dwivedi

    • Innate like T cells in Rheumatoid Arthritis and Other Autoimmune Arthritis Dr. Helena Jonsson

      Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.

    October 27th

    • Accelerating skin disease research by Dr. Rachael Clark

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    September 29th

    • Discovering the pro- and anti-regenerative factors at work post-amputation by Dr. Jessica Whited

      Human Cartilage Aging and Osteoarthritis by Dr. Shuanhu Zhou

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    July 21st

    • Classification of adult and pediatric arthritis and Year 1 JBC roundup and feedback session by Dr. Peter Nigrovic

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    May 23rd

    JBC’s First Annual Visiting Speaker: Dr. Michael Holers

    • Rheumatology Grand Rounds

      Studies of At-Risk Populations Provide Insights into the Origins and Pathogenesis of Pre-Clinical Rheumatoid Arthritis

      Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.
    • Patient Care Rounds

      Are We Ready for Prevention of Rheumatoid Arthritis?

      Location:  Room 5010- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.

    April 28th

    • Exploration of myeloid cell biology using Hoxb8 cells. by Dr. Pui Lee

    • Translational Research using Patient Samples and Data by Dr. Yvonne Lee

    Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
    Time: 12:30-1:30 p.m.

    February 17th

    • Introduction to Boston Children’s Hospital Biorepositories by Dr. Lauren Henderson

    • RNAseq-driven differentiation of neutrophil subsets defined via CD177 by Ricardo Grieshaber

      Location:  Room 02006B- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.

    January

    • Introduction to RNA-sew by Dr. Chad Nusbaum

    • Application of RNA sequencing in RA research and Data Analysis by Dr. Kevin Wei and Kamil Slowikowski

    • Location:  Room 3014- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115

      Time: 12:30-1:30 p.m.

    2016

    December

    • Using the Partners Biobank Portal for research studies by Dr. Elizabeth Karlson

    • Clinical research tools using the electronic medical record: natural language processing (NLP) and phenome-wide association study (PheWAS) By Dr. Jeffrey Sparks

      Location:  Room 6014- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.

    October

    • JBC Updates by Dr. Peter Nigrovic
    • Introduction to CyTOF by Dr. Jim Lederer

    • CyTOF Application in Research by Dr. Deepak Rao

    • Location:  Room 3014- Building of Transformative Medicine (BTM),  60 Fenwood Road, Boston, MA 02115
      Time: 12:30-1:30 p.m.

    September

    • Introducing the NIAMS-funded Joint Biology Consortium (JBC) by Drs. Peter Nigrovic and Elizabeth Karlson

    Location:  Room 546- Large Conference Room, Smith Building, 1 Jimmy Fund Way, Boston, MA 02115
    Time: 12:30-1:30 p.m.
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